Solvent-Free Preparation of Novel 2-[Phenyl (Pyridine-2-Ylamino) Methyl] Phenols as Pseudo-Betti Processor for Natural Products
نویسندگان
چکیده
منابع مشابه
solvent-free preparation of novel 2-[phenyl (pyridine-2-ylamino) methyl] phenols as pseudo-betti processor for natural products
conclusions we have developed a new, simple, and efficient method for one-pot aminoalkylation of active phenol compounds with various imines prepared from 2-aminopyrimidine and benzaldehydes in good to high yields (40%-97%). materials and methods all starting materials were purchased from merck and aldrich companies. the ir spectra were recorded on a perkin-elmer rxi infrared spectrometer. resu...
متن کاملSolvent-Free Preparation of Novel 2-[Phenyl (Pyridine-2-Ylamino) Methyl] Phenols as Pseudo-Betti Processor for Natural Products
BACKGROUND 2-Aminopyridine and benzaldehydes mixture readily reacted with phenols at 80°C without any solvents to produce novel 2-[phenyl (pyridine-2-yl amino (methyl] phenol derivatives as pseudo-Betti products in good to high yields. These compounds are efficient processor for synthesis of the natural products. OBJECTIVES We decided to report the synthesis of a series of novel N-heteroaryl-...
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An efficient synthesis of Methyl 2-[2-(alkylimino)-4-oxo-3-phenyl-1,3-thiazolan-5-yliden]acetate derivatives via simple three-component reaction and one-pot reactions between isoquinoline, dimethyl acetylenedicarboxylate and N-phenylthiourea under solvent-free conditions without using any additional catalyst, is described. The mild reaction conditions and good yields and exhibit the synthetic a...
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In the title compound, C(23)H(22)N(4)O, the pyrazole ring makes dihedral angles of 45.57 (11)° with the attached phenyl ring, and 83.98 (10) and 67.85 (10) °, respectively, with the other phenyl ring and the pyridyl ring. The pyridyl ring makes a dihedral angle of 80.15 (10)° with the adjacent phenyl ring. In the crystal, N-H⋯O hydrogen bonds supplemented by weak C-H⋯O hydrogen bonds link the m...
متن کاملsynthesis of methyl 2-[2-(alkylimino)-4-oxo-3-phenyl-1,3-thiazolan-5-yliden]acetate derivatives under solvent-free condition
an efficient synthesis of methyl 2-[2-(alkylimino)-4-oxo-3-phenyl-1,3-thiazolan-5-yliden]acetate derivatives via simple three-component reaction and one-pot reactions between isoquinoline, dimethyl acetylenedicarboxylate and n-phenylthiourea under solvent-free conditions without using any additional catalyst, is described. the mild reaction conditions and good yields and exhibit the synthetic a...
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ژورنال
عنوان ژورنال: Jundishapur Journal of Natural Pharmaceutical Products
سال: 2014
ISSN: 1735-7780,2228-7876
DOI: 10.17795/jjnpp-17808